BDBM50267260 1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2-(2-(trifluoromethyl)phenyl)ethanone::CHEMBL514697

SMILES: FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)S(=O)(=O)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=ZJDHNKQXFQFOCP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267260 (1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2...) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)S(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C19H17Cl2F3N2O3S/c20-14-10-15(21)12-16(11-14)30(28,29)26-7-5-25(6-8-26)18(27)9-13-3-1-2-4-17(13)19(22,23)24/h1-4,10-12H,5-9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP level				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267260 (1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2...) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCN(CC1)S(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C19H17Cl2F3N2O3S/c20-14-10-15(21)12-16(11-14)30(28,29)26-7-5-25(6-8-26)18(27)9-13-3-1-2-4-17(13)19(22,23)24/h1-4,10-12H,5-9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cells				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair