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SMILES: CC(C)C[C@H](NC(=O)c1cc2cc(OP(O)(O)=O)ccc2[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

InChI Key: InChIKey=KJEJOOXWIJYVOZ-KUVQTUHOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267442   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))		BDBM50267442
PNG
(CHEMBL485921 | pInd-Leu-Pro-Gln-Thr-NH2)
Show SMILES CC(C)C[C@H](NC(=O)c1cc2cc(OP(O)(O)=O)ccc2[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
Show InChI InChI=1S/C29H42N7O11P/c1-14(2)11-21(34-27(41)20-13-16-12-17(47-48(44,45)46)6-7-18(16)32-20)29(43)36-10-4-5-22(36)28(42)33-19(8-9-23(30)38)26(40)35-24(15(3)37)25(31)39/h6-7,12-15,19,21-22,24,32,37H,4-5,8-11H2,1-3H3,(H2,30,38)(H2,31,39)(H,33,42)(H,34,41)(H,35,40)(H2,44,45,46)/t15-,19+,21+,22+,24+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 186n/an/an/an/an/an/a



The University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inhibition of Stat3 (unknown origin) by fluorescence polarization assay

J Med Chem 52: 2429-42 (2009)


Article DOI: 10.1021/jm801491w
BindingDB Entry DOI: 10.7270/Q28C9W4V
More data for this
Ligand-Target Pair