BDBM50267508 4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine::CHEMBL516088

SMILES: COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1

InChI Key: InChIKey=HVJOIRMQZXEGPW-UHFFFAOYSA-N

Data: 26 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50267508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyser				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5-HT2C receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned alpha1A adrenergic receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	174	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned dopamine D4 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT7 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned alpha2C adrenergic receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned alpha1B adrenergic receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	713	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1D receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	863	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned alpha2A adrenergic receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	944	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned histamine H1 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT2B receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned dopamine D1 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT5A receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1A receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned histamine H2 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1B receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned SERT by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned dopamine D2 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned dopamine D5 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT6 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned histamine H3 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned beta3 adrenergic receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned mu opioid receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned DAT by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1E receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50267508 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...) Show SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT3 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair