BDBM50267571 CHEMBL489032::[1-(2-Aminoethyl)-1-azoniabicyclo[2.2.2]oct-4-yl](diphenyl)-methanolate bromide

SMILES: NCC[N+]12CCC(CC1)(CC2)C(O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=DEDANTMTMALIQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50267571 (CHEMBL489032 | [1-(2-Aminoethyl)-1-azoniabicyclo[2...) Show SMILES NCC[N+]12CCC(CC1)(CC2)C(O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H29N2O/c23-14-18-24-15-11-21(12-16-24,13-17-24)22(25,19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-10,25H,11-18,23H2/q+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...				J Med Chem 52: 2493-505 (2009) Article DOI: 10.1021/jm801601v BindingDB Entry DOI: 10.7270/Q2H131X8
					More data for this Ligand-Target Pair