null

SMILES: O=C1Cc2ccccc2N1CC#CCN1CCN(CC1)c1cccc2ccccc12

InChI Key: InChIKey=XYQICMLZHAIYGB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267783 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...) Show SMILES O=C1Cc2ccccc2N1CC#CCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H25N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-4,7-13H,14-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267783 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...) Show SMILES O=C1Cc2ccccc2N1CC#CCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H25N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-4,7-13H,14-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair