BDBM50267809 4-(Hydroxy{bis[3-(methyloxy)phenyl]}methyl)-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane Bromide::CHEMBL523767

SMILES: COc1cccc(c1)C(O)(c1cccc(OC)c1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2

InChI Key: InChIKey=XMUDNHXQYYVLNN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50267809 (4-(Hydroxy{bis[3-(methyloxy)phenyl]}methyl)-1-{2-[...) Show SMILES COc1cccc(c1)C(O)(c1cccc(OC)c1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2 Show InChI InChI=1S/C31H38NO4/c1-34-28-12-6-10-26(22-28)31(33,27-11-7-13-29(23-27)35-2)30-14-17-32(18-15-30,19-16-30)20-21-36-24-25-8-4-3-5-9-25/h3-13,22-23,33H,14-21,24H2,1-2H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...				J Med Chem 52: 2493-505 (2009) Article DOI: 10.1021/jm801601v BindingDB Entry DOI: 10.7270/Q2H131X8
					More data for this Ligand-Target Pair