BDBM50267986 (+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-2-[4-(methyloxy)-phenyl]ethyl)amino)-2-propanol::CHEMBL491251

SMILES: COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1

InChI Key: InChIKey=DWAKJSOEJNKPME-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50267986 ((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...) Show SMILES COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 Show InChI InChI=1S/C20H25Cl2NO3/c1-20(2,11-14-7-9-16(25-3)10-8-14)23-12-15(24)13-26-18-6-4-5-17(21)19(18)22/h4-10,15,23-24H,11-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to beta2 adrenoceptor				J Med Chem 52: 3982-93 (2009) Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50267986 ((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...) Show SMILES COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 Show InChI InChI=1S/C20H25Cl2NO3/c1-20(2,11-14-7-9-16(25-3)10-8-14)23-12-15(24)13-26-18-6-4-5-17(21)19(18)22/h4-10,15,23-24H,11-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to beta3 adrenoceptor				J Med Chem 52: 3982-93 (2009) Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X
					More data for this Ligand-Target Pair
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50267986 ((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...) Show SMILES COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 Show InChI InChI=1S/C20H25Cl2NO3/c1-20(2,11-14-7-9-16(25-3)10-8-14)23-12-15(24)13-26-18-6-4-5-17(21)19(18)22/h4-10,15,23-24H,11-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay				J Med Chem 52: 3982-93 (2009) Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X
					More data for this Ligand-Target Pair