Found 8 hits for monomerid = 50267987 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to beta2 adrenoceptor |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to beta3 adrenoceptor |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to serotonin transporter |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Calcium-sensing receptor (CaSR)
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to dopamine transporter |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to norepinephrine transporter |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to human ERG |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)Show InChI InChI=1S/C21H26N2O3/c1-21(2,12-16-8-10-19(25-3)11-9-16)23-14-18(24)15-26-20-7-5-4-6-17(20)13-22/h4-11,18,23-24H,12,14-15H2,1-3H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Binding affinity to CYP2D6 |
J Med Chem 52: 3982-93 (2009)
Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X |
More data for this Ligand-Target Pair | |