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BDBM50268054 (+/-)-[3-[(2,3-Dichlorophenyl)oxy]-2-(methyloxy)propyl](1,1-dimethyl-2-[4-(methyloxy)phenyl]ethyl)amine::CHEMBL488738

SMILES: COC(CNC(C)(C)Cc1ccc(OC)cc1)COc1cccc(Cl)c1Cl

InChI Key: InChIKey=GLXMMOOGCALSDK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268054   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))		BDBM50268054
PNG
((+/-)-[3-[(2,3-Dichlorophenyl)oxy]-2-(methyloxy)pr...)
Show SMILES COC(CNC(C)(C)Cc1ccc(OC)cc1)COc1cccc(Cl)c1Cl
Show InChI InChI=1S/C21H27Cl2NO3/c1-21(2,12-15-8-10-16(25-3)11-9-15)24-13-17(26-4)14-27-19-7-5-6-18(22)20(19)23/h5-11,17,24H,12-14H2,1-4H3
PDB

UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 950n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay

J Med Chem 52: 3982-93 (2009)


Article DOI: 10.1021/jm900364m
BindingDB Entry DOI: 10.7270/Q2M61K5X
More data for this
Ligand-Target Pair