BDBM50268270 (+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethyl)amino)-3-(2-naphthalenyloxy)-2-propanol::CHEMBL487511

SMILES: COc1ccc(CC(C)(C)NCC(O)COc2ccc3ccccc3c2)cc1

InChI Key: InChIKey=RKYYDYRRRMHWHW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50268270 ((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...) Show SMILES COc1ccc(CC(C)(C)NCC(O)COc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C24H29NO3/c1-24(2,15-18-8-11-22(27-3)12-9-18)25-16-21(26)17-28-23-13-10-19-6-4-5-7-20(19)14-23/h4-14,21,25-26H,15-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay				J Med Chem 52: 3982-93 (2009) Article DOI: 10.1021/jm900364m BindingDB Entry DOI: 10.7270/Q2M61K5X
					More data for this Ligand-Target Pair