BDBM50268885 CHEMBL4084508

SMILES: COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C(C)C

InChI Key: InChIKey=RINVPEJSDRLKKC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein G9a (G9a) (Homo sapiens (Human))	BDBM50268885 (CHEMBL4084508) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C(C)C Show InChI InChI=1S/C20H31N5O2/c1-13(2)25(4)20-22-16-12-18(27-6)17(26-5)11-15(16)19(23-20)21-14-7-9-24(3)10-8-14/h11-14H,7-10H2,1-6H3,(H,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	318	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human G9a catalytic domain (913 to 1193 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268885 (CHEMBL4084508) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C(C)C Show InChI InChI=1S/C20H31N5O2/c1-13(2)25(4)20-22-16-12-18(27-6)17(26-5)11-15(16)19(23-20)21-14-7-9-24(3)10-8-14/h11-14H,7-10H2,1-6H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair