BDBM50268952 (2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)piperidine-3-carboxamide::CHEMBL496211

SMILES: CN1CC(CC(=O)N2CCCCC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO

InChI Key: InChIKey=VOGZLMQCZGOADJ-FLJXZVEISA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50268952 ((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...) Show SMILES CN1CC(CC(=O)N2CCCCC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C25H37N5O4/c1-27-18-19(17-22(31)29-10-6-3-7-11-29)16-21(24(32)26-34)23(27)25(33)30-14-12-28(13-15-30)20-8-4-2-5-9-20/h2,4-5,8-9,19,21,23,34H,3,6-7,10-18H2,1H3,(H,26,32)/t19?,21-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISA				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50268952 ((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...) Show SMILES CN1CC(CC(=O)N2CCCCC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C25H37N5O4/c1-27-18-19(17-22(31)29-10-6-3-7-11-29)16-21(24(32)26-34)23(27)25(33)30-14-12-28(13-15-30)20-8-4-2-5-9-20/h2,4-5,8-9,19,21,23,34H,3,6-7,10-18H2,1H3,(H,26,32)/t19?,21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human MMP2				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) (Homo sapiens (Human))	BDBM50268952 ((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...) Show SMILES CN1CC(CC(=O)N2CCCCC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C25H37N5O4/c1-27-18-19(17-22(31)29-10-6-3-7-11-29)16-21(24(32)26-34)23(27)25(33)30-14-12-28(13-15-30)20-8-4-2-5-9-20/h2,4-5,8-9,19,21,23,34H,3,6-7,10-18H2,1H3,(H,26,32)/t19?,21-,23-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM10				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair