Found 4 hits for monomerid = 50269974 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Parathyroid hormone receptor
(Homo sapiens (Human)) | BDBM50269974
(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r,wU:79.79,25.25,47.48,60.59,8.12,38.38,96.96,wD:29.34,16.21,91.92,70.70,53.53,105.105,43.43,4.4,(19.79,-32.24,;18.45,-31.5,;18.43,-29.97,;17.09,-29.22,;17.07,-27.69,;15.77,-26.88,;14.41,-27.6,;14.41,-29.15,;13.14,-26.73,;13.14,-25.19,;14.47,-24.42,;14.47,-22.88,;15.8,-25.19,;11.92,-27.63,;10.55,-26.91,;10.56,-25.36,;9.28,-27.78,;9.28,-29.32,;10.62,-30.09,;10.62,-31.62,;9.28,-32.4,;11.94,-32.4,;8.07,-26.88,;6.71,-27.62,;6.71,-29.17,;5.43,-26.75,;4.22,-27.65,;2.86,-26.93,;2.87,-25.38,;1.59,-27.79,;1.59,-29.33,;2.92,-30.11,;2.92,-31.64,;1.59,-32.42,;4.25,-32.42,;.38,-26.9,;-.98,-27.63,;-.97,-29.17,;-2.25,-26.76,;-2.25,-25.22,;-3.47,-27.64,;-4.82,-26.91,;-4.82,-25.37,;-6.11,-27.78,;-7.32,-26.89,;-8.68,-27.62,;-8.67,-29.16,;-9.96,-26.75,;-9.96,-25.21,;-11.17,-27.64,;-6.11,-29.33,;-4.78,-30.1,;-7.44,-30.1,;5.43,-25.21,;6.76,-24.44,;4.09,-24.43,;4.08,-22.89,;18.25,-26.9,;18.27,-25.35,;19.62,-27.63,;20.84,-26.74,;20.84,-25.2,;22.17,-24.42,;23.64,-24.92,;24.55,-23.68,;23.66,-22.42,;22.19,-22.88,;22.12,-27.61,;22.12,-29.15,;23.47,-26.88,;24.69,-27.77,;24.69,-29.31,;26.02,-30.09,;26.02,-31.62,;24.69,-32.39,;27.36,-32.39,;25.97,-26.9,;25.98,-25.36,;27.34,-27.63,;28.55,-26.74,;28.55,-25.2,;29.89,-24.43,;29.89,-22.89,;31.22,-22.12,;31.22,-20.59,;32.54,-19.82,;32.54,-18.29,;33.87,-20.59,;29.83,-27.61,;29.83,-29.15,;31.19,-26.88,;32.4,-27.78,;32.4,-29.32,;33.68,-26.91,;33.68,-25.36,;35.04,-27.64,;36.26,-26.75,;36.26,-25.2,;37.59,-24.43,;37.6,-22.89,;38.92,-22.13,;38.92,-20.59,;37.54,-27.61,;37.55,-29.16,;38.9,-26.88,;40.24,-27.61,;40.27,-29.14,;41.61,-29.88,;41.64,-31.41,;42.98,-32.15,;44.29,-31.36,;45.63,-32.09,;44.25,-29.82,;42.91,-29.09,;41.55,-26.82,;42.89,-27.55,;41.52,-25.28,)| Show InChI InChI=1S/C75H125N23O19/c1-11-13-18-47(91-71(114)54(33-38(3)4)95-69(112)51(26-29-57(79)101)93-74(117)60(40(7)12-2)98-70(113)52(27-30-58(102)103)89-64(107)43(10)87-73(116)59(39(5)6)97-62(105)41(8)77)67(110)96-55(35-45-36-83-37-85-45)72(115)92-50(25-28-56(78)100)68(111)90-48(20-15-17-32-84-75(81)82)65(108)86-42(9)63(106)88-49(19-14-16-31-76)66(109)94-53(61(80)104)34-44-21-23-46(99)24-22-44/h21-24,36-43,47-55,59-60,99H,11-20,25-35,76-77H2,1-10H3,(H2,78,100)(H2,79,101)(H2,80,104)(H,83,85)(H,86,108)(H,87,116)(H,88,106)(H,89,107)(H,90,111)(H,91,114)(H,92,115)(H,93,117)(H,94,109)(H,95,112)(H,96,110)(H,97,105)(H,98,113)(H,102,103)(H4,81,82,84)/t40-,41-,42-,43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59-,60-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cells |
Proc Natl Acad Sci U S A 104: 6846-51 (2007)
Article DOI: 10.1073/pnas.0605125104
BindingDB Entry DOI: 10.7270/Q28P608V |
More data for this
Ligand-Target Pair | |
Parathyroid hormone receptor
(Homo sapiens (Human)) | BDBM50269974
(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r,wU:79.79,25.25,47.48,60.59,8.12,38.38,96.96,wD:29.34,16.21,91.92,70.70,53.53,105.105,43.43,4.4,(19.79,-32.24,;18.45,-31.5,;18.43,-29.97,;17.09,-29.22,;17.07,-27.69,;15.77,-26.88,;14.41,-27.6,;14.41,-29.15,;13.14,-26.73,;13.14,-25.19,;14.47,-24.42,;14.47,-22.88,;15.8,-25.19,;11.92,-27.63,;10.55,-26.91,;10.56,-25.36,;9.28,-27.78,;9.28,-29.32,;10.62,-30.09,;10.62,-31.62,;9.28,-32.4,;11.94,-32.4,;8.07,-26.88,;6.71,-27.62,;6.71,-29.17,;5.43,-26.75,;4.22,-27.65,;2.86,-26.93,;2.87,-25.38,;1.59,-27.79,;1.59,-29.33,;2.92,-30.11,;2.92,-31.64,;1.59,-32.42,;4.25,-32.42,;.38,-26.9,;-.98,-27.63,;-.97,-29.17,;-2.25,-26.76,;-2.25,-25.22,;-3.47,-27.64,;-4.82,-26.91,;-4.82,-25.37,;-6.11,-27.78,;-7.32,-26.89,;-8.68,-27.62,;-8.67,-29.16,;-9.96,-26.75,;-9.96,-25.21,;-11.17,-27.64,;-6.11,-29.33,;-4.78,-30.1,;-7.44,-30.1,;5.43,-25.21,;6.76,-24.44,;4.09,-24.43,;4.08,-22.89,;18.25,-26.9,;18.27,-25.35,;19.62,-27.63,;20.84,-26.74,;20.84,-25.2,;22.17,-24.42,;23.64,-24.92,;24.55,-23.68,;23.66,-22.42,;22.19,-22.88,;22.12,-27.61,;22.12,-29.15,;23.47,-26.88,;24.69,-27.77,;24.69,-29.31,;26.02,-30.09,;26.02,-31.62,;24.69,-32.39,;27.36,-32.39,;25.97,-26.9,;25.98,-25.36,;27.34,-27.63,;28.55,-26.74,;28.55,-25.2,;29.89,-24.43,;29.89,-22.89,;31.22,-22.12,;31.22,-20.59,;32.54,-19.82,;32.54,-18.29,;33.87,-20.59,;29.83,-27.61,;29.83,-29.15,;31.19,-26.88,;32.4,-27.78,;32.4,-29.32,;33.68,-26.91,;33.68,-25.36,;35.04,-27.64,;36.26,-26.75,;36.26,-25.2,;37.59,-24.43,;37.6,-22.89,;38.92,-22.13,;38.92,-20.59,;37.54,-27.61,;37.55,-29.16,;38.9,-26.88,;40.24,-27.61,;40.27,-29.14,;41.61,-29.88,;41.64,-31.41,;42.98,-32.15,;44.29,-31.36,;45.63,-32.09,;44.25,-29.82,;42.91,-29.09,;41.55,-26.82,;42.89,-27.55,;41.52,-25.28,)| Show InChI InChI=1S/C75H125N23O19/c1-11-13-18-47(91-71(114)54(33-38(3)4)95-69(112)51(26-29-57(79)101)93-74(117)60(40(7)12-2)98-70(113)52(27-30-58(102)103)89-64(107)43(10)87-73(116)59(39(5)6)97-62(105)41(8)77)67(110)96-55(35-45-36-83-37-85-45)72(115)92-50(25-28-56(78)100)68(111)90-48(20-15-17-32-84-75(81)82)65(108)86-42(9)63(106)88-49(19-14-16-31-76)66(109)94-53(61(80)104)34-44-21-23-46(99)24-22-44/h21-24,36-43,47-55,59-60,99H,11-20,25-35,76-77H2,1-10H3,(H2,78,100)(H2,79,101)(H2,80,104)(H,83,85)(H,86,108)(H,87,116)(H,88,106)(H,89,107)(H,90,111)(H,91,114)(H,92,115)(H,93,117)(H,94,109)(H,95,112)(H,96,110)(H,97,105)(H,98,113)(H,102,103)(H4,81,82,84)/t40-,41-,42-,43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59-,60-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ... |
Proc Natl Acad Sci U S A 104: 6846-51 (2007)
Article DOI: 10.1073/pnas.0605125104
BindingDB Entry DOI: 10.7270/Q28P608V |
More data for this
Ligand-Target Pair | |
Parathyroid hormone 1 receptor (PTH1R)
(Rattus norvegicus (Rat)) | BDBM50269974
(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r,wU:79.79,25.25,47.48,60.59,8.12,38.38,96.96,wD:29.34,16.21,91.92,70.70,53.53,105.105,43.43,4.4,(19.79,-32.24,;18.45,-31.5,;18.43,-29.97,;17.09,-29.22,;17.07,-27.69,;15.77,-26.88,;14.41,-27.6,;14.41,-29.15,;13.14,-26.73,;13.14,-25.19,;14.47,-24.42,;14.47,-22.88,;15.8,-25.19,;11.92,-27.63,;10.55,-26.91,;10.56,-25.36,;9.28,-27.78,;9.28,-29.32,;10.62,-30.09,;10.62,-31.62,;9.28,-32.4,;11.94,-32.4,;8.07,-26.88,;6.71,-27.62,;6.71,-29.17,;5.43,-26.75,;4.22,-27.65,;2.86,-26.93,;2.87,-25.38,;1.59,-27.79,;1.59,-29.33,;2.92,-30.11,;2.92,-31.64,;1.59,-32.42,;4.25,-32.42,;.38,-26.9,;-.98,-27.63,;-.97,-29.17,;-2.25,-26.76,;-2.25,-25.22,;-3.47,-27.64,;-4.82,-26.91,;-4.82,-25.37,;-6.11,-27.78,;-7.32,-26.89,;-8.68,-27.62,;-8.67,-29.16,;-9.96,-26.75,;-9.96,-25.21,;-11.17,-27.64,;-6.11,-29.33,;-4.78,-30.1,;-7.44,-30.1,;5.43,-25.21,;6.76,-24.44,;4.09,-24.43,;4.08,-22.89,;18.25,-26.9,;18.27,-25.35,;19.62,-27.63,;20.84,-26.74,;20.84,-25.2,;22.17,-24.42,;23.64,-24.92,;24.55,-23.68,;23.66,-22.42,;22.19,-22.88,;22.12,-27.61,;22.12,-29.15,;23.47,-26.88,;24.69,-27.77,;24.69,-29.31,;26.02,-30.09,;26.02,-31.62,;24.69,-32.39,;27.36,-32.39,;25.97,-26.9,;25.98,-25.36,;27.34,-27.63,;28.55,-26.74,;28.55,-25.2,;29.89,-24.43,;29.89,-22.89,;31.22,-22.12,;31.22,-20.59,;32.54,-19.82,;32.54,-18.29,;33.87,-20.59,;29.83,-27.61,;29.83,-29.15,;31.19,-26.88,;32.4,-27.78,;32.4,-29.32,;33.68,-26.91,;33.68,-25.36,;35.04,-27.64,;36.26,-26.75,;36.26,-25.2,;37.59,-24.43,;37.6,-22.89,;38.92,-22.13,;38.92,-20.59,;37.54,-27.61,;37.55,-29.16,;38.9,-26.88,;40.24,-27.61,;40.27,-29.14,;41.61,-29.88,;41.64,-31.41,;42.98,-32.15,;44.29,-31.36,;45.63,-32.09,;44.25,-29.82,;42.91,-29.09,;41.55,-26.82,;42.89,-27.55,;41.52,-25.28,)| Show InChI InChI=1S/C75H125N23O19/c1-11-13-18-47(91-71(114)54(33-38(3)4)95-69(112)51(26-29-57(79)101)93-74(117)60(40(7)12-2)98-70(113)52(27-30-58(102)103)89-64(107)43(10)87-73(116)59(39(5)6)97-62(105)41(8)77)67(110)96-55(35-45-36-83-37-85-45)72(115)92-50(25-28-56(78)100)68(111)90-48(20-15-17-32-84-75(81)82)65(108)86-42(9)63(106)88-49(19-14-16-31-76)66(109)94-53(61(80)104)34-44-21-23-46(99)24-22-44/h21-24,36-43,47-55,59-60,99H,11-20,25-35,76-77H2,1-10H3,(H2,78,100)(H2,79,101)(H2,80,104)(H,83,85)(H,86,108)(H,87,116)(H,88,106)(H,89,107)(H,90,111)(H,91,114)(H,92,115)(H,93,117)(H,94,109)(H,95,112)(H,96,110)(H,97,105)(H,98,113)(H,102,103)(H4,81,82,84)/t40-,41-,42-,43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59-,60-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 344 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formation |
Proc Natl Acad Sci U S A 104: 6846-51 (2007)
Article DOI: 10.1073/pnas.0605125104
BindingDB Entry DOI: 10.7270/Q28P608V |
More data for this
Ligand-Target Pair | |
Parathyroid hormone receptor
(Homo sapiens (Human)) | BDBM50269974
(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r,wU:79.79,25.25,47.48,60.59,8.12,38.38,96.96,wD:29.34,16.21,91.92,70.70,53.53,105.105,43.43,4.4,(19.79,-32.24,;18.45,-31.5,;18.43,-29.97,;17.09,-29.22,;17.07,-27.69,;15.77,-26.88,;14.41,-27.6,;14.41,-29.15,;13.14,-26.73,;13.14,-25.19,;14.47,-24.42,;14.47,-22.88,;15.8,-25.19,;11.92,-27.63,;10.55,-26.91,;10.56,-25.36,;9.28,-27.78,;9.28,-29.32,;10.62,-30.09,;10.62,-31.62,;9.28,-32.4,;11.94,-32.4,;8.07,-26.88,;6.71,-27.62,;6.71,-29.17,;5.43,-26.75,;4.22,-27.65,;2.86,-26.93,;2.87,-25.38,;1.59,-27.79,;1.59,-29.33,;2.92,-30.11,;2.92,-31.64,;1.59,-32.42,;4.25,-32.42,;.38,-26.9,;-.98,-27.63,;-.97,-29.17,;-2.25,-26.76,;-2.25,-25.22,;-3.47,-27.64,;-4.82,-26.91,;-4.82,-25.37,;-6.11,-27.78,;-7.32,-26.89,;-8.68,-27.62,;-8.67,-29.16,;-9.96,-26.75,;-9.96,-25.21,;-11.17,-27.64,;-6.11,-29.33,;-4.78,-30.1,;-7.44,-30.1,;5.43,-25.21,;6.76,-24.44,;4.09,-24.43,;4.08,-22.89,;18.25,-26.9,;18.27,-25.35,;19.62,-27.63,;20.84,-26.74,;20.84,-25.2,;22.17,-24.42,;23.64,-24.92,;24.55,-23.68,;23.66,-22.42,;22.19,-22.88,;22.12,-27.61,;22.12,-29.15,;23.47,-26.88,;24.69,-27.77,;24.69,-29.31,;26.02,-30.09,;26.02,-31.62,;24.69,-32.39,;27.36,-32.39,;25.97,-26.9,;25.98,-25.36,;27.34,-27.63,;28.55,-26.74,;28.55,-25.2,;29.89,-24.43,;29.89,-22.89,;31.22,-22.12,;31.22,-20.59,;32.54,-19.82,;32.54,-18.29,;33.87,-20.59,;29.83,-27.61,;29.83,-29.15,;31.19,-26.88,;32.4,-27.78,;32.4,-29.32,;33.68,-26.91,;33.68,-25.36,;35.04,-27.64,;36.26,-26.75,;36.26,-25.2,;37.59,-24.43,;37.6,-22.89,;38.92,-22.13,;38.92,-20.59,;37.54,-27.61,;37.55,-29.16,;38.9,-26.88,;40.24,-27.61,;40.27,-29.14,;41.61,-29.88,;41.64,-31.41,;42.98,-32.15,;44.29,-31.36,;45.63,-32.09,;44.25,-29.82,;42.91,-29.09,;41.55,-26.82,;42.89,-27.55,;41.52,-25.28,)| Show InChI InChI=1S/C75H125N23O19/c1-11-13-18-47(91-71(114)54(33-38(3)4)95-69(112)51(26-29-57(79)101)93-74(117)60(40(7)12-2)98-70(113)52(27-30-58(102)103)89-64(107)43(10)87-73(116)59(39(5)6)97-62(105)41(8)77)67(110)96-55(35-45-36-83-37-85-45)72(115)92-50(25-28-56(78)100)68(111)90-48(20-15-17-32-84-75(81)82)65(108)86-42(9)63(106)88-49(19-14-16-31-76)66(109)94-53(61(80)104)34-44-21-23-46(99)24-22-44/h21-24,36-43,47-55,59-60,99H,11-20,25-35,76-77H2,1-10H3,(H2,78,100)(H2,79,101)(H2,80,104)(H,83,85)(H,86,108)(H,87,116)(H,88,106)(H,89,107)(H,90,111)(H,91,114)(H,92,115)(H,93,117)(H,94,109)(H,95,112)(H,96,110)(H,97,105)(H,98,113)(H,102,103)(H4,81,82,84)/t40-,41-,42-,43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59-,60-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formation |
Proc Natl Acad Sci U S A 104: 6846-51 (2007)
Article DOI: 10.1073/pnas.0605125104
BindingDB Entry DOI: 10.7270/Q28P608V |
More data for this
Ligand-Target Pair | |
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