BDBM50270212 CHEMBL509337::GAGAGATPRARRRKKRT

SMILES: [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7])-[#6@@H](-[#6])-[#8])-[#6](-[#8])=O

InChI Key: InChIKey=DZXZMKHZXPDGBH-WEXWTDDCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Furin (Homo sapiens (Human))	BDBM50270212 (CHEMBL509337 | GAGAGATPRARRRKKRT) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7])-[#6@@H](-[#6])-[#8])-[#6](-[#8])=O |r| Show InChI InChI=1S/C73H136N34O20/c1-36(94-50(110)33-76)55(113)92-34-51(111)95-37(2)56(114)93-35-52(112)96-38(3)58(116)105-53(40(5)108)67(125)107-32-16-24-49(107)66(124)104-44(19-11-27-87-69(77)78)59(117)97-39(4)57(115)98-45(20-12-28-88-70(79)80)62(120)101-47(22-14-30-90-72(83)84)64(122)102-46(21-13-29-89-71(81)82)63(121)100-42(17-7-9-25-74)60(118)99-43(18-8-10-26-75)61(119)103-48(23-15-31-91-73(85)86)65(123)106-54(41(6)109)68(126)127/h36-49,53-54,108-109H,7-35,74-76H2,1-6H3,(H,92,113)(H,93,114)(H,94,110)(H,95,111)(H,96,112)(H,97,117)(H,98,115)(H,99,118)(H,100,121)(H,101,120)(H,102,122)(H,103,119)(H,104,124)(H,105,116)(H,106,123)(H,126,127)(H4,77,78,87)(H4,79,80,88)(H4,81,82,89)(H4,83,84,90)(H4,85,86,91)/t36-,37-,38-,39-,40+,41+,42-,43-,44-,45-,46-,47-,48-,49-,53-,54-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant furin assessed as fluorescent Pyr-RTKR-AMC substrate cleavage				J Biol Chem 282: 20847-53 (2007) Article DOI: 10.1074/jbc.M703847200 BindingDB Entry DOI: 10.7270/Q2057FPB
					More data for this Ligand-Target Pair