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BDBM50270323 3-(3'-Quinolyl)-quinuclidine-2-ene::CHEMBL478340

SMILES: C1CN2CCC1C(=C2)c1cnc2ccccc2c1

InChI Key: InChIKey=WNZRVIBSBSVTIR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270323   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Farnesyltransferase, putative


(Leishmania major)		BDBM50270323
PNG
(3-(3'-Quinolyl)-quinuclidine-2-ene | CHEMBL478340)
Show SMILES C1CN2CCC1C(=C2)c1cnc2ccccc2c1 |c:7,(20.51,-11.4,;20.51,-12.95,;21.84,-13.72,;22.59,-12.38,;21.11,-11.98,;21.84,-10.63,;23.18,-11.4,;23.18,-12.95,;24.51,-10.64,;25.84,-11.41,;27.17,-10.64,;27.17,-9.1,;28.5,-8.33,;28.5,-6.79,;27.15,-6.02,;25.83,-6.8,;25.83,-8.33,;24.51,-9.1,)|
Show InChI InChI=1S/C16H16N2/c1-2-4-16-13(3-1)9-14(10-17-16)15-11-18-7-5-12(15)6-8-18/h1-4,9-12H,5-8H2
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counter

Antimicrob Agents Chemother 51: 4049-61 (2007)


Article DOI: 10.1128/AAC.00205-07
BindingDB Entry DOI: 10.7270/Q2MS3SJZ
More data for this
Ligand-Target Pair