BDBM50270339 (2R,3S,4S,5R)-2-((cyclobutylamino)methyl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol::CHEMBL472122

SMILES: OC[C@H]1O[C@H](CNC2CCC2)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=QSEBBWHKFWHLFF-ZYUZMQFOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase (Leishmania mexicana)	BDBM50270339 ((2R,3S,4S,5R)-2-((cyclobutylamino)methyl)-5-(hydro...) Show SMILES OC[C@H]1O[C@H](CNC2CCC2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H19NO4/c12-5-8-10(14)9(13)7(15-8)4-11-6-2-1-3-6/h6-14H,1-5H2/t7-,8-,9-,10-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of Leishmania mexicana pyruvate kinase				Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR
					More data for this Ligand-Target Pair