BDBM50270526 7-Ethynyl-1H-indazole::CHEMBL452956

SMILES: C#Cc1cccc2cn[nH]c12

InChI Key: InChIKey=RZRGQMHAEDLRBS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM50270526 (7-Ethynyl-1H-indazole | CHEMBL452956) Show SMILES C#Cc1cccc2cn[nH]c12 Show InChI InChI=1S/C9H6N2/c1-2-7-4-3-5-8-6-10-11-9(7)8/h1,3-6H,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of rat brain recombinant nNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, endothelial (Bos taurus (bovine))	BDBM50270526 (7-Ethynyl-1H-indazole | CHEMBL452956) Show SMILES C#Cc1cccc2cn[nH]c12 Show InChI InChI=1S/C9H6N2/c1-2-7-4-3-5-8-6-10-11-9(7)8/h1,3-6H,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50270526 (7-Ethynyl-1H-indazole | CHEMBL452956) Show SMILES C#Cc1cccc2cn[nH]c12 Show InChI InChI=1S/C9H6N2/c1-2-7-4-3-5-8-6-10-11-9(7)8/h1,3-6H,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair