BDBM50270528 3-BROMO-7-NITROINDAZOLE::3-bromo-7-nitro-1H-indazole::CHEMBL479014

SMILES: [O-][N+](=O)c1cccc2c(Br)n[nH]c12

InChI Key: InChIKey=NFSTZPMYAZRZPC-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50270528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of rat brain recombinant nNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
UNED Curated by ChEMBL					Assay Description Inhibition of NOS2				Bioorg Med Chem 17: 6180-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.067 BindingDB Entry DOI: 10.7270/Q2ZG6SBD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
UNED Curated by ChEMBL					Assay Description Inhibition of NOS1				Bioorg Med Chem 17: 6180-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.067 BindingDB Entry DOI: 10.7270/Q2ZG6SBD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric Oxide Synthase, endothelial (Bos taurus (bovine))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair				3D Structure (crystal)