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BDBM50270683 5-(4-Chlorophenyl)furan-2-carboxylic acid (1-methylpiperidine-dine-4-yl)amide::CHEMBL487308

SMILES: CN1CCC(CC1)NC(=O)c1ccc(o1)-c1ccc(Cl)cc1

InChI Key: InChIKey=PAMVKPQNNLSWGJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270683   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type X alpha subunit


(Mus musculus)
BDBM50270683
PNG
(5-(4-Chlorophenyl)furan-2-carboxylic acid (1-methy...)
Show SMILES CN1CCC(CC1)NC(=O)c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H19ClN2O2/c1-20-10-8-14(9-11-20)19-17(21)16-7-6-15(22-16)12-2-4-13(18)5-3-12/h2-7,14H,8-11H2,1H3,(H,19,21)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay


Bioorg Med Chem 16: 6379-86 (2008)


Article DOI: 10.1016/j.bmc.2008.05.003
BindingDB Entry DOI: 10.7270/Q2VH5NNT
More data for this
Ligand-Target Pair