BDBM50270705 5-(4-Chlorophenyl)furan-2-carboxylic acid (3-dimethylamino-2,2-dimethylpropyl)amide::CHEMBL450458

SMILES: CN(C)CC(C)(C)CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1

InChI Key: InChIKey=CNZJYNXLIROXSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Mus musculus)	BDBM50270705 (5-(4-Chlorophenyl)furan-2-carboxylic acid (3-dimet...) Show SMILES CN(C)CC(C)(C)CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H23ClN2O2/c1-18(2,12-21(3)4)11-20-17(22)16-10-9-15(23-16)13-5-7-14(19)8-6-13/h5-10H,11-12H2,1-4H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay				Bioorg Med Chem 16: 6379-86 (2008) Article DOI: 10.1016/j.bmc.2008.05.003 BindingDB Entry DOI: 10.7270/Q2VH5NNT
					More data for this Ligand-Target Pair