BDBM50271570 1-[4-Chlorophenylsulfonyl]-4-[3-(pyridin-4-yl)phenylmethyl]-piperazine::CHEMBL482523

SMILES: Clc1ccc(cc1)S(=O)(=O)N1CCN(Cc2cccc(c2)-c2ccncc2)CC1

InChI Key: InChIKey=CHUJGKLCCMSDCY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50271570 (1-[4-Chlorophenylsulfonyl]-4-[3-(pyridin-4-yl)phen...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CCN(Cc2cccc(c2)-c2ccncc2)CC1 Show InChI InChI=1S/C22H22ClN3O2S/c23-21-4-6-22(7-5-21)29(27,28)26-14-12-25(13-15-26)17-18-2-1-3-20(16-18)19-8-10-24-11-9-19/h1-11,16H,12-15,17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)				Bioorg Med Chem 16: 6218-32 (2008) Article DOI: 10.1016/j.bmc.2008.04.034 BindingDB Entry DOI: 10.7270/Q2M61K14
					More data for this Ligand-Target Pair