BDBM50271620 1-[4-Chlorophenylsulfonyl]-4-[4-(dimethylaminomethyl)phenylmethyl]-piperazine::CHEMBL521168

SMILES: CN(C)Cc1ccc(CN2CCN(CC2)S(=O)(=O)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=DGAWUPZWGOHIQW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50271620 (1-[4-Chlorophenylsulfonyl]-4-[4-(dimethylaminometh...) Show SMILES CN(C)Cc1ccc(CN2CCN(CC2)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H26ClN3O2S/c1-22(2)15-17-3-5-18(6-4-17)16-23-11-13-24(14-12-23)27(25,26)20-9-7-19(21)8-10-20/h3-10H,11-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)				Bioorg Med Chem 16: 6218-32 (2008) Article DOI: 10.1016/j.bmc.2008.04.034 BindingDB Entry DOI: 10.7270/Q2M61K14
					More data for this Ligand-Target Pair