Found 3 hits for monomerid = 50272013 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50272013
(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)Show SMILES Nc1nccc(Oc2ccc(NC(=O)NC(=O)Cc3ccc(F)cc3)cc2F)c1C#CCO Show InChI InChI=1S/C23H18F2N4O4/c24-15-5-3-14(4-6-15)12-21(31)29-23(32)28-16-7-8-20(18(25)13-16)33-19-9-10-27-22(26)17(19)2-1-11-30/h3-10,13,30H,11-12H2,(H2,26,27)(H2,28,29,31,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Met kinase (unknown origin) |
Bioorg Med Chem Lett 18: 3224-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.047
BindingDB Entry DOI: 10.7270/Q2XG9QX1 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50272013
(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)Show SMILES Nc1nccc(Oc2ccc(NC(=O)NC(=O)Cc3ccc(F)cc3)cc2F)c1C#CCO Show InChI InChI=1S/C23H18F2N4O4/c24-15-5-3-14(4-6-15)12-21(31)29-23(32)28-16-7-8-20(18(25)13-16)33-19-9-10-27-22(26)17(19)2-1-11-30/h3-10,13,30H,11-12H2,(H2,26,27)(H2,28,29,31,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description
Inhibition of human c-MET |
Eur J Med Chem 46: 3675-80 (2011)
Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50272013
(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)Show SMILES Nc1nccc(Oc2ccc(NC(=O)NC(=O)Cc3ccc(F)cc3)cc2F)c1C#CCO Show InChI InChI=1S/C23H18F2N4O4/c24-15-5-3-14(4-6-15)12-21(31)29-23(32)28-16-7-8-20(18(25)13-16)33-19-9-10-27-22(26)17(19)2-1-11-30/h3-10,13,30H,11-12H2,(H2,26,27)(H2,28,29,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 18: 3224-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.047
BindingDB Entry DOI: 10.7270/Q2XG9QX1 |
More data for this
Ligand-Target Pair | |
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