BDBM50272175 CHEMBL499628::N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanamide

SMILES: CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12

InChI Key: InChIKey=LWGMCCRZWULJJR-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272175 (CHEMBL499628 | N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN4O2/c1-2-30-21-6-4-3-5-19(21)20-15-18(11-12-22(20)30)27-23(31)13-14-24-28-25(29-32-24)16-7-9-17(26)10-8-16/h3-12,15H,2,13-14H2,1H3,(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair