BDBM50272197 2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-phenyl-2-(pyrrolidin-1-ylmethyl)piperazin-1-yl)ethanone::CHEMBL502267

SMILES: CN(CC(=O)N1CCN(CC1CN1CCCC1)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=YCQVUICBLXERSU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50272197 (2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-phenyl-...) Show SMILES CN(CC(=O)N1CCN(CC1CN1CCCC1)c1ccccc1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H30Cl2N4O/c1-27(20-9-10-22(25)23(26)15-20)18-24(31)30-14-13-29(19-7-3-2-4-8-19)17-21(30)16-28-11-5-6-12-28/h2-4,7-10,15,21H,5-6,11-14,16-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assay				Bioorg Med Chem Lett 18: 4470-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.067 BindingDB Entry DOI: 10.7270/Q2TH8MHF
					More data for this Ligand-Target Pair