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BDBM50272364 9-hydroxy-4-(4-(methylsulfonyl)phenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL526721

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cc2[nH]c3ccc(O)cc3c2c2C(=O)NC(=O)c12

InChI Key: InChIKey=TVSZXXQPRYYWQG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272364   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase WEE1


(Homo sapiens (Human))
BDBM50272364
PNG
(9-hydroxy-4-(4-(methylsulfonyl)phenyl)pyrrolo[3,4-...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc2[nH]c3ccc(O)cc3c2c2C(=O)NC(=O)c12
Show InChI InChI=1S/C21H14N2O5S/c1-29(27,28)12-5-2-10(3-6-12)13-9-16-17(19-18(13)20(25)23-21(19)26)14-8-11(24)4-7-15(14)22-16/h2-9,22,24H,1H3,(H,23,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.12E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of human Wee1


Eur J Med Chem 44: 1383-95 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.027
BindingDB Entry DOI: 10.7270/Q2X34XB6
More data for this
Ligand-Target Pair