BDBM50272392 5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)isoxazol-3-amine::CHEMBL500670

SMILES: CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1

InChI Key: InChIKey=ZPMCQPHGBGPKNX-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272392 (5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2...) Show SMILES CC(C)(C)c1cc(NCCCc2nc(no2)-c2ccc(F)cc2Cl)no1 Show InChI InChI=1S/C18H20ClFN4O2/c1-18(2,3)14-10-15(23-25-14)21-8-4-5-16-22-17(24-26-16)12-7-6-11(20)9-13(12)19/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair