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SMILES: O=C(Cn1c2ccccc2oc1=O)N1CCN(CC1CN1CCCC1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=YOOCPUSFCXBQHY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272412   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50272412
PNG
(3-(2-oxo-2-(4-(phenylsulfonyl)-2-(pyrrolidin-1-ylm...)
Show SMILES O=C(Cn1c2ccccc2oc1=O)N1CCN(CC1CN1CCCC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H28N4O5S/c29-23(18-28-21-10-4-5-11-22(21)33-24(28)30)27-15-14-26(17-19(27)16-25-12-6-7-13-25)34(31,32)20-8-2-1-3-9-20/h1-5,8-11,19H,6-7,12-18H2
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Similars
Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assay

Bioorg Med Chem Lett 18: 4470-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.067
BindingDB Entry DOI: 10.7270/Q2TH8MHF
More data for this
Ligand-Target Pair