BDBM50272430 3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butyl)quinoline::CHEMBL498470

SMILES: Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1

InChI Key: InChIKey=FSUSWHJMGXMKBV-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272430 (3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCCc3ccc4ncccc4c3)n2)c(Cl)c1 Show InChI InChI=1S/C21H17ClFN3O/c22-18-13-16(23)8-9-17(18)21-25-20(27-26-21)6-2-1-4-14-7-10-19-15(12-14)5-3-11-24-19/h3,5,7-13H,1-2,4,6H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair