BDBM50272448 2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-((dimethylamino)methyl)chroman-4-yl)acetamide::CHEMBL504119

SMILES: CN(C)Cc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@H]1N(c2ccccc2NC1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=QPWTWPRYKWNPJJ-RCZVLFRGSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50272448 (2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...) Show SMILES CN(C)Cc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@H]1N(c2ccccc2NC1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C28H28Cl2N4O5S/c1-33(2)16-17-7-9-19-22(11-12-39-26(19)13-17)31-27(35)15-25-28(36)32-23-5-3-4-6-24(23)34(25)40(37,38)18-8-10-20(29)21(30)14-18/h3-10,13-14,22,25H,11-12,15-16H2,1-2H3,(H,31,35)(H,32,36)/t22-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration technique				Bioorg Med Chem Lett 18: 4477-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.055 BindingDB Entry DOI: 10.7270/Q2F76CCT
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50272448 (2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...) Show SMILES CN(C)Cc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@H]1N(c2ccccc2NC1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C28H28Cl2N4O5S/c1-33(2)16-17-7-9-19-22(11-12-39-26(19)13-17)31-27(35)15-25-28(36)32-23-5-3-4-6-24(23)34(25)40(37,38)18-8-10-20(29)21(30)14-18/h3-10,13-14,22,25H,11-12,15-16H2,1-2H3,(H,31,35)(H,32,36)/t22-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells				Bioorg Med Chem Lett 18: 4477-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.055 BindingDB Entry DOI: 10.7270/Q2F76CCT
					More data for this Ligand-Target Pair