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BDBM50272601 CHEMBL498324::N-(9-Ethyl-9H-carbazol-3-yl)-3-(5-(2-fluorophenyl)-1H-pyrazol-3-yl)propanamide

SMILES: CCn1c2ccccc2c2cc(NC(=O)CCc3cc(n[nH]3)-c3ccccc3F)ccc12

InChI Key: InChIKey=AINAOCGEWHJMQA-UHFFFAOYSA-N

Data: 2 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272601   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50272601
PNG
(CHEMBL498324 | N-(9-Ethyl-9H-carbazol-3-yl)-3-(5-(...)
Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3cc(n[nH]3)-c3ccccc3F)ccc12
Show InChI InChI=1S/C26H23FN4O/c1-2-31-24-10-6-4-7-19(24)21-15-17(11-13-25(21)31)28-26(32)14-12-18-16-23(30-29-18)20-8-3-5-9-22(20)27/h3-11,13,15-16H,2,12,14H2,1H3,(H,28,32)(H,29,30)
PDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay


J Med Chem 51: 5019-34 (2008)


Article DOI: 10.1021/jm800463f
BindingDB Entry DOI: 10.7270/Q2W096VS
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50272601
PNG
(CHEMBL498324 | N-(9-Ethyl-9H-carbazol-3-yl)-3-(5-(...)
Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3cc(n[nH]3)-c3ccccc3F)ccc12
Show InChI InChI=1S/C26H23FN4O/c1-2-31-24-10-6-4-7-19(24)21-15-17(11-13-25(21)31)28-26(32)14-12-18-16-23(30-29-18)20-8-3-5-9-22(20)27/h3-11,13,15-16H,2,12,14H2,1H3,(H,28,32)(H,29,30)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay


J Med Chem 51: 5019-34 (2008)


Article DOI: 10.1021/jm800463f
BindingDB Entry DOI: 10.7270/Q2W096VS
More data for this
Ligand-Target Pair