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SMILES: CCCN(CCC)c1c(C)nc(nc1OC)-c1c(OC)cc(cc1C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=RNLLRUKOJDSQAN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272702   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50272702
PNG
(4-methoxy-2-(2-methoxy-4,6-bis(trifluoromethyl)phe...)
Show SMILES CCCN(CCC)c1c(C)nc(nc1OC)-c1c(OC)cc(cc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C21H25F6N3O2/c1-6-8-30(9-7-2)17-12(3)28-18(29-19(17)32-5)16-14(21(25,26)27)10-13(20(22,23)24)11-15(16)31-4/h10-11H,6-9H2,1-5H3
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MMDB

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Article
PubMed
 6n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cells

Bioorg Med Chem Lett 18: 4486-90 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.063
BindingDB Entry DOI: 10.7270/Q2NG4RJ4
More data for this
Ligand-Target Pair