null

SMILES: NCc1n[nH]c(=O)o1

InChI Key: InChIKey=BGFKDHCRDPQSGH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50273002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha1beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.82E+5	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha2beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3 (RAT)	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+6	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha3beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6 (RAT)	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membrane				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha5beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6 (RAT)	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha6beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50273002 (5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...) Show SMILES NCc1n[nH]c(=O)o1 Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Agonist activity at rat recombinant GABAAalpha4beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
					More data for this Ligand-Target Pair