null

SMILES: CC(C)(C)c1ccc(cc1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1

InChI Key: InChIKey=NYSSYBPYKWNMSG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273023 (1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...) Show SMILES CC(C)(C)c1ccc(cc1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C24H29N3O3/c1-24(2,3)17-4-7-19(8-5-17)27-12-10-16(11-13-27)23(29)25-18-6-9-21-20(14-18)26-22(28)15-30-21/h4-9,14,16H,10-13,15H2,1-3H3,(H,25,29)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273023 (1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...) Show SMILES CC(C)(C)c1ccc(cc1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C24H29N3O3/c1-24(2,3)17-4-7-19(8-5-17)27-12-10-16(11-13-27)23(29)25-18-6-9-21-20(14-18)26-22(28)15-30-21/h4-9,14,16H,10-13,15H2,1-3H3,(H,25,29)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPR				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair