null

SMILES: Fc1cc(cc(F)c1F)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1

InChI Key: InChIKey=YDSQPCYZGZKQPK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273058 (CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...) Show SMILES Fc1cc(cc(F)c1F)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H18F3N3O3/c21-14-8-13(9-15(22)19(14)23)26-5-3-11(4-6-26)20(28)24-12-1-2-17-16(7-12)25-18(27)10-29-17/h1-2,7-9,11H,3-6,10H2,(H,24,28)(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273058 (CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...) Show SMILES Fc1cc(cc(F)c1F)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H18F3N3O3/c21-14-8-13(9-15(22)19(14)23)26-5-3-11(4-6-26)20(28)24-12-1-2-17-16(7-12)25-18(27)10-29-17/h1-2,7-9,11H,3-6,10H2,(H,24,28)(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPR				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair