BDBM50273191 3-[2-(4-Isopropyl-phenyl)-ethylsulfamoyl]-4-methoxy-benzamidine::CHEMBL457392
SMILES: COc1ccc(cc1S(=O)(=O)NCCc1ccc(cc1)C(C)C)C(N)=N
InChI Key: InChIKey=DGZLWYDZOJFNEA-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50273191 (3-[2-(4-Isopropyl-phenyl)-ethylsulfamoyl]-4-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human factor 10a by Dixon-plot method | Bioorg Med Chem Lett 18: 4682-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.009 BindingDB Entry DOI: 10.7270/Q208654H | |||||||||||
More data for this Ligand-Target Pair |