BDBM50273264 CHEMBL457632::ethyl 2-(2-(2-(2-hydroxy-5-(N'-hydroxycarbamimidoyl)phenylsulfonamido)ethyl)-5-isopropylphenoxy)acetate

SMILES: CCOC(=O)COc1cc(ccc1CCNS(=O)(=O)c1cc(ccc1O)C(=N)NO)C(C)C

InChI Key: InChIKey=CCESNYTWBYWRQB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50273264 (CHEMBL457632 | ethyl 2-(2-(2-(2-hydroxy-5-(N'-hydr...) Show SMILES CCOC(=O)COc1cc(ccc1CCNS(=O)(=O)c1cc(ccc1O)C(=N)NO)C(C)C Show InChI InChI=1S/C22H29N3O7S/c1-4-31-21(27)13-32-19-11-16(14(2)3)6-5-15(19)9-10-24-33(29,30)20-12-17(22(23)25-28)7-8-18(20)26/h5-8,11-12,14,24,26,28H,4,9-10,13H2,1-3H3,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a by Dixon-plot method				Bioorg Med Chem Lett 18: 4682-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.009 BindingDB Entry DOI: 10.7270/Q208654H
					More data for this Ligand-Target Pair