BDBM50273450 CHEMBL509257::N-Cyclopentyl-4-{2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methyl-4-oxo-4,5-dihydrothiazol-5-yl}benzamide

SMILES: C[C@H](NC1=NC(=O)C(C)(S1)c1ccc(cc1)C(=O)NC1CCCC1)c1ccc(F)cc1

InChI Key: InChIKey=IMPHNPDXLUQXTE-FZADBTJQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50273450 (CHEMBL509257 | N-Cyclopentyl-4-{2-[(S)-1-(4-fluoro...) Show SMILES C[C@H](NC1=NC(=O)C(C)(S1)c1ccc(cc1)C(=O)NC1CCCC1)c1ccc(F)cc1 |r,t:3| Show InChI InChI=1S/C24H26FN3O2S/c1-15(16-9-13-19(25)14-10-16)26-23-28-22(30)24(2,31-23)18-11-7-17(8-12-18)21(29)27-20-5-3-4-6-20/h7-15,20H,3-6H2,1-2H3,(H,27,29)(H,26,28,30)/t15-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assay				J Med Chem 51: 7953-67 (2008) Article DOI: 10.1021/jm801073z BindingDB Entry DOI: 10.7270/Q2FJ2GN7
					More data for this Ligand-Target Pair