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BDBM50273488 CHEMBL464798::N-Methyl, N-phenyl-1-methyl-1H-indole-2-carboxamide

SMILES: CN(C(=O)c1cc2ccccc2n1C)c1ccccc1

InChI Key: InChIKey=BWRCVGRVYKKDEW-UHFFFAOYSA-N

Data: 3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273488   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Bos taurus)
BDBM50273488
PNG
(CHEMBL464798 | N-Methyl, N-phenyl-1-methyl-1H-indo...)
Show SMILES CN(C(=O)c1cc2ccccc2n1C)c1ccccc1
Show InChI InChI=1S/C17H16N2O/c1-18(14-9-4-3-5-10-14)17(20)16-12-13-8-6-7-11-15(13)19(16)2/h3-12H,1-2H3
PDB
MMDB

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Article
PubMed
15n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273488
PNG
(CHEMBL464798 | N-Methyl, N-phenyl-1-methyl-1H-indo...)
Show SMILES CN(C(=O)c1cc2ccccc2n1C)c1ccccc1
Show InChI InChI=1S/C17H16N2O/c1-18(14-9-4-3-5-10-14)17(20)16-12-13-8-6-7-11-15(13)19(16)2/h3-12H,1-2H3
PDB
MMDB

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21n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Amine oxidase (flavin-containing) A


(Homo sapiens (Human))
BDBM50273488
PNG
(CHEMBL464798 | N-Methyl, N-phenyl-1-methyl-1H-indo...)
Show SMILES CN(C(=O)c1cc2ccccc2n1C)c1ccccc1
Show InChI InChI=1S/C17H16N2O/c1-18(14-9-4-3-5-10-14)17(20)16-12-13-8-6-7-11-15(13)19(16)2/h3-12H,1-2H3
PDB

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UniProtKB/TrEMBL

antibodypedia
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Article
PubMed
1.50E+7n/an/an/an/an/an/an/an/a



Bharati Vidyapeeth Deemed University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A receptor


Bioorg Med Chem Lett 21: 2419-24 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.072
BindingDB Entry DOI: 10.7270/Q2QZ2C6S
More data for this
Ligand-Target Pair