BDBM50273717 CHEMBL504429::[2-(Imidazol-2-yl-thio)ethyl]-bisphosphonic acid

SMILES: OP(O)(=O)C(CSc1ncc[nH]1)P(O)(O)=O

InChI Key: InChIKey=KVMQBCIVXMEYRO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl diphosphate synthase (Homo sapiens (Human))	BDBM50273717 (CHEMBL504429 | [2-(Imidazol-2-yl-thio)ethyl]-bisph...) Show SMILES OP(O)(=O)C(CSc1ncc[nH]1)P(O)(O)=O Show InChI InChI=1S/C5H10N2O6P2S/c8-14(9,10)4(15(11,12)13)3-16-5-6-1-2-7-5/h1-2,4H,3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28.1	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Ferrara Curated by ChEMBL					Assay Description Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)				J Med Chem 51: 6800-7 (2008) Article DOI: 10.1021/jm801003y BindingDB Entry DOI: 10.7270/Q2F76CD8
					More data for this Ligand-Target Pair