BDBM50273818 6-Bromo-N-(naphthalen-2-yl)-2-(pyridin-3-yl)quinoline-4-carboxamide::CHEMBL456184

SMILES: Brc1ccc2nc(cc(C(=O)Nc3ccc4ccccc4c3)c2c1)-c1cccnc1

InChI Key: InChIKey=SYZSHYVQKXQTTJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50273818 (6-Bromo-N-(naphthalen-2-yl)-2-(pyridin-3-yl)quinol...) Show SMILES Brc1ccc2nc(cc(C(=O)Nc3ccc4ccccc4c3)c2c1)-c1cccnc1 Show InChI InChI=1S/C25H16BrN3O/c26-19-8-10-23-21(13-19)22(14-24(29-23)18-6-3-11-27-15-18)25(30)28-20-9-7-16-4-1-2-5-17(16)12-20/h1-15H,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of reconstituted CYP2C9 (unknown origin)				J Med Chem 51: 8000-11 (2008) Article DOI: 10.1021/jm8011257 BindingDB Entry DOI: 10.7270/Q2K937CZ
					More data for this Ligand-Target Pair