BDBM50273974 3-fluoro-2-oxopropanoate
SMILES: [O-]C(=O)C(=O)CF
InChI Key: InChIKey=CXABZTLXNODUTD-UHFFFAOYSA-M
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrodipicolinate synthase (Escherichia coli (strain K12)) | BDBM50273974 (3-fluoro-2-oxopropanoate) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents | Article PubMed | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Melbourne Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DHDPS | Bioorg Med Chem 16: 9975-83 (2008) Article DOI: 10.1016/j.bmc.2008.10.026 BindingDB Entry DOI: 10.7270/Q2FN1748 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mandelate racemase (MR) (Pseudomonas putida (g-Proteobacteria)) | BDBM50273974 (3-fluoro-2-oxopropanoate) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents | Article PubMed | 1.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Dalhousie University | Assay Description MR activity was assayed using a CD-based assay by following the change in ellipticity of mandelate at 262 nm using a thermostated quartz cuvette with... | Biochemistry 54: 2747-57 (2015) Article DOI: 10.1021/acs.biochem.5b00221 BindingDB Entry DOI: 10.7270/Q2ZK5FDT | |||||||||||
More data for this Ligand-Target Pair |