BDBM50274236 2-(trimethylsilyl)ethyl (5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2,6)-beta-D-galactopyranoside)::CHEMBL456656

SMILES: CC(=O)N[C@@H]1[C@@H](O)C[C@@](OC[C@H]2O[C@@H](Oc3ccc(OCC[Si](C)(C)C)cc3)[C@H](O)[C@@H](O)[C@H]2O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

InChI Key: InChIKey=URLSRYOITCOCSU-OYQSBWFESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell receptor CD22 (Homo sapiens (Human))	BDBM50274236 (2-(trimethylsilyl)ethyl (5-acetamido-3,5-dideoxy-D...) Show SMILES CC(=O)N[C@@H]1[C@@H](O)C[C@@](OC[C@H]2O[C@@H](Oc3ccc(OCC[Si](C)(C)C)cc3)[C@H](O)[C@@H](O)[C@H]2O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O |r| Show InChI InChI=1S/C28H45NO15Si/c1-14(31)29-20-17(32)11-28(27(38)39,44-25(20)21(34)18(33)12-30)41-13-19-22(35)23(36)24(37)26(43-19)42-16-7-5-15(6-8-16)40-9-10-45(2,3)4/h5-8,17-26,30,32-37H,9-13H2,1-4H3,(H,29,31)(H,38,39)/t17-,18+,19+,20+,21+,22-,23-,24+,25+,26+,28+/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gifu University Curated by ChEMBL					Assay Description Binding affinity to biotinylated human CD22-human IgG1 chimeric protein expressed in mouse J558LST6 cells by flow cytometry				J Med Chem 51: 6665-81 (2008) Article DOI: 10.1021/jm8000696 BindingDB Entry DOI: 10.7270/Q23X86GN
					More data for this Ligand-Target Pair