BDBM50274351 2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyridin-3-yl)-N,N-dipropylacetamide::CHEMBL520465

SMILES: CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=HFLZKYYKRXMNPI-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50274351 (2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...) Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22Cl2N4O3/c1-3-9-25(10-4-2)19(28)12-18-20(14-5-7-16(8-6-14)27(29)30)24-21-17(23)11-15(22)13-26(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting				J Med Chem 51: 6876-88 (2008) Article DOI: 10.1021/jm8006728 BindingDB Entry DOI: 10.7270/Q23B612K
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50274351 (2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...) Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22Cl2N4O3/c1-3-9-25(10-4-2)19(28)12-18-20(14-5-7-16(8-6-14)27(29)30)24-21-17(23)11-15(22)13-26(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Inhibition of TSPO (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50274351 (2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...) Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22Cl2N4O3/c1-3-9-25(10-4-2)19(28)12-18-20(14-5-7-16(8-6-14)27(29)30)24-21-17(23)11-15(22)13-26(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Inhibition of TSPO (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569
					More data for this Ligand-Target Pair