BindingDB PrimarySearch

BDBM50274460 CHEMBL504540::FGGFTGARKSARKYANQ::OFQ/N,[Tyr14]

SMILES: [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](-[#8])=O

InChI Key: InChIKey=NTZGMAAQXGNGFH-VDVVPONDSA-N

Data: 2 KI 1 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274460
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nociceptin/Orphanin FQ, NOP receptor (MOUSE)	BDBM50274460 (CHEMBL504540 \| FGGFTGARKSARKYANQ \| OFQ/N,[Tyr14]) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by PDSP K_i Database									Pharmacol Rev 53: 381-415 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7FWB
McGill University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin/Orphanin FQ, NOP receptor (MOUSE)	BDBM50274460 (CHEMBL504540 \| FGGFTGARKSARKYANQ \| OFQ/N,[Tyr14]) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by PDSP K_i Database									Pharmacol Rev 53: 381-415 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7FWB
McGill University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin/Orphanin FQ, NOP receptor (RAT)	BDBM50274460 (CHEMBL504540 \| FGGFTGARKSARKYANQ \| OFQ/N,[Tyr14]) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells				Bioorg Med Chem 16: 9261-7 (2008) Article DOI: 10.1016/j.bmc.2008.09.014 BindingDB Entry DOI: 10.7270/Q2MC90XH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin/Orphanin FQ, NOP receptor (RAT)	BDBM50274460 (CHEMBL504540 \| FGGFTGARKSARKYANQ \| OFQ/N,[Tyr14]) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem 16: 9261-7 (2008) Article DOI: 10.1016/j.bmc.2008.09.014 BindingDB Entry DOI: 10.7270/Q2MC90XH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair