BDBM50274579 3-(4-[(1-Isopropyl-4-piperidinyl)oxy]phenyl)-2-methyl-4(3H)-quinazolinone::CHEMBL519839

SMILES: CC(C)N1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=PYTUDUDDLQDLRW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50274579 (3-(4-[(1-Isopropyl-4-piperidinyl)oxy]phenyl)-2-met...) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O Show InChI InChI=1S/C23H27N3O2/c1-16(2)25-14-12-20(13-15-25)28-19-10-8-18(9-11-19)26-17(3)24-22-7-5-4-6-21(22)23(26)27/h4-11,16,20H,12-15H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...				J Med Chem 51: 6889-901 (2008) Article DOI: 10.1021/jm800569w BindingDB Entry DOI: 10.7270/Q27P8Z60
					More data for this Ligand-Target Pair