BDBM50274618 3-(4-[(1-Cyclohexyl-4-piperidinyl)oxy]phenyl)-2-methyl-4(3H)-quinazolinone::CHEMBL483367

SMILES: Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCN(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=JTMUYOVETWILBX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50274618 (3-(4-[(1-Cyclohexyl-4-piperidinyl)oxy]phenyl)-2-me...) Show SMILES Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCN(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C26H31N3O2/c1-19-27-25-10-6-5-9-24(25)26(30)29(19)21-11-13-22(14-12-21)31-23-15-17-28(18-16-23)20-7-3-2-4-8-20/h5-6,9-14,20,23H,2-4,7-8,15-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...				J Med Chem 51: 6889-901 (2008) Article DOI: 10.1021/jm800569w BindingDB Entry DOI: 10.7270/Q27P8Z60
					More data for this Ligand-Target Pair