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SMILES: CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2cnc(C)n2C)cc1

InChI Key: InChIKey=HIKMYPBLGKUYLS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274663   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 2


(Homo sapiens (Human))		BDBM50274663
PNG
(4-(4-(1,2-dimethyl-1H-imidazol-5-yl)pyrimidin-2-yl...)
Show SMILES CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2cnc(C)n2C)cc1
Show InChI InChI=1S/C19H25N7O2S/c1-14-21-13-18(26(14)4)17-9-10-20-19(24-17)23-15-5-7-16(8-6-15)29(27,28)22-11-12-25(2)3/h5-10,13,22H,11-12H2,1-4H3,(H,20,23,24)
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MMDB

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n/an/a 25n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of CDK2

Bioorg Med Chem Lett 18: 5487-92 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.024
BindingDB Entry DOI: 10.7270/Q2J9667K
More data for this
Ligand-Target Pair