BDBM50274891 (Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazolidin-4-one::CHEMBL456850

SMILES: SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1

InChI Key: InChIKey=ATGWUPYXIYFRKP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50274891 ((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...) Show SMILES SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1 |w:7.8,t:1| Show InChI InChI=1S/C14H9NOS2/c16-13-12(18-14(17)15-13)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H,(H,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair
Arylamine N-acetyltransferase 2 (Mus musculus)	BDBM50274891 ((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...) Show SMILES SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1 |w:7.8,t:1| Show InChI InChI=1S/C14H9NOS2/c16-13-12(18-14(17)15-13)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H,(H,15,16,17)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method				Bioorg Med Chem 17: 905-18 (2009) Article DOI: 10.1016/j.bmc.2008.11.032 BindingDB Entry DOI: 10.7270/Q2PZ58Q3
					More data for this Ligand-Target Pair