BDBM50275256 CHEMBL485939::[3,5-Dimethyl-4-(4'-hydroxy-3'-phenylbenzyl)phenoxy]methylphosphonicAcid

SMILES: Cc1cc(OCP(O)(O)=O)cc(C)c1Cc1ccc(O)c(c1)-c1ccccc1

InChI Key: InChIKey=GDGHGXAILIZPNP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50275256 (CHEMBL485939 | [3,5-Dimethyl-4-(4'-hydroxy-3'-phen...) Show SMILES Cc1cc(OCP(O)(O)=O)cc(C)c1Cc1ccc(O)c(c1)-c1ccccc1 Show InChI InChI=1S/C22H23O5P/c1-15-10-19(27-14-28(24,25)26)11-16(2)20(15)12-17-8-9-22(23)21(13-17)18-6-4-3-5-7-18/h3-11,13,23H,12,14H2,1-2H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay				J Med Chem 51: 7075-93 (2009) Article DOI: 10.1021/jm800824d BindingDB Entry DOI: 10.7270/Q21V5DT5
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50275256 (CHEMBL485939 | [3,5-Dimethyl-4-(4'-hydroxy-3'-phen...) Show SMILES Cc1cc(OCP(O)(O)=O)cc(C)c1Cc1ccc(O)c(c1)-c1ccccc1 Show InChI InChI=1S/C22H23O5P/c1-15-10-19(27-14-28(24,25)26)11-16(2)20(15)12-17-8-9-22(23)21(13-17)18-6-4-3-5-7-18/h3-11,13,23H,12,14H2,1-2H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assay				J Med Chem 51: 7075-93 (2009) Article DOI: 10.1021/jm800824d BindingDB Entry DOI: 10.7270/Q21V5DT5
					More data for this Ligand-Target Pair